It is frequently found on the heavy metal assay many years after imaging studies, in spite of the fact that, supposedly, it is said to leave the body within hours. If you've ever had an MRI with contrast before, then there's a likelihood that you have some levels of the lanthanide element gadolinium stored in your body and/or brain. R, For example, in a case study, Gd has shown to cause encephalopathy. Although NSF has essentially vanished as a disease by judicious selection of patients and avoiding high/multiple doses, recent attention concerning free gadolinium in tissues has caused us to switch exclusively to macrocyclic agents. They had told me before I made this journey that they could help us. Repeated exposure to Gd has shown to accumulate in the body and brain and increase the risk of gd-related toxicity by increasing inflammation in the tissue it is in. If you have poor kidney function, gadolinium may not be properly removed and remain as a toxin in your system. R, Insoluble deposits containing Gd3+ have been found in brain tumors following contrast-enhanced MRI. R. Hi I'm Jacob!I started MyBioHack because after being sick, doctors could no longer help me. R, It also may directly induce cell death (necrosis and apoptosis). may help to prevent cancer. The Cutler protocol is safe. To those who suffer from Gadolinium Toxicity and other heavy metal toxicity etc. Following The Recommended Protocol Of Dr. David E. Root. What is a Safe Heavy Metal Detox Protocol and Detox Cycle? R, Gd agents (GBACs) consist of a central paramagnetic Gd3+ chelated to a ligand to prevent direct toxicity by free Gd3+. R. Having no Gd levels is good and repeated exposure can increase retention in the body. R, Gd3+ concentration was significantly higher (180-fold) in rats skin that received gadodiamide than in those treated with gadoteric acid. I usually do not post this kind of thinking on the support group because many people hold out chelation as their only hope. TRS removes any toxin with a positive charge COMPLETELY OUT of the body (unlike chlorella) and includes: aluminum, mercury, arsenic, fluoride, barium, strontium, uranium, lead, and others gadolinium (considered a heavy metal) a very common toxin used as a contrast agent in MRIs pesticides and herbicides (incl Roundup/glyphosate) Next, we need to discuss the length and cycling of DMSA during a protocol. I have visited ERs and hospitals during my adventure to regain my health and have had my fair share of scans. When you get MRIs as often as my kids do (every 3-6 months) detoxing is a must. It causes the MRI scanner to highlight certain body structures better than if the MRI is done without the gadolinium contrast medium. The strongest approach is with intravenous (IV) infusion of a chelating agent(s) by a doctor. For example, it is necessary to take this oral chelator for at least 4 days before you stop. R, Gd can easily (slowly) pass through and/or disrupt the blood-brain barrier (BBB). R, However, in Gd3+ all the electrons have parallel spin and this property is important for the use of gadolinium complexes as contrast reagent in MRI scans. I say that from many years (22) of experience. R, Gd3+ can induce allosteric activation of the G-protein-coupled calcium-sensing receptor (CaSR). R GBCAs allowed up to see the body light up during scans and … It then needs to be separated in order to be used for the agents (or dyes) that are used during MRIs. This is specifically why I created my Myers Detox Protocol. R, http://www.physiology.org/doi/10.1152/ajprenal.00166.2016, In animal models exposed to Gd, their skin had more scarring and swelling. If you opted in to the Get Detoxinated!™ Program, then you will need the ability to weigh yourself, take regular blood pressure readings, body temperature, BMI (Body Mass Index) and fat percent. Unfortunately, conventional medicine ignores the role of heavy metals as cause of chronic diseases. R. Testing in the hair or blood can also performed (get hair test done here). It is only slightly malleable and is a ductile rare-earth element. How to Cure your GDD - YouTube R, Pregnancy can lead to mobilization of Gd from bone through the placenta into the fetus. R, It can also increase TG, LDL, and VLDL levels while reducing HDL levels. Zeolite, a natural mineral, is uniquely suited to remove toxic chemicals. Here you can find the strongest tactics science has to offer in overcoming and improving chronic disease. Doing a liver and kidney cleanse is beneficial as well. Gadolinium is one of Earth’s elements, with it coming in the rare metal section. Gd in GBCAs was originally believed to be excreted by the body, but unfortunately we have discovered that Gd may accumulate in tissue, since GBCAs stability may deposit free Gd (Gd3+) into tissue. R, Free Gd3+ is a toxic lanthanide heavy metal with a size similar to that of Ca2+. It took doctors 9 years to find that it was mercury poisoning. R, It also reduces nitric oxide (NO) bioavailability. R R, Gd has shown to cause acute pancreatitis. This allows the radiologist (a specialist doctor trained to examine the images and provide a written report to your doctor or specialist) to more accurately report on how your body is working and whether there is any disease o… 1) First – Get a Good Whack of Chlorella – Light sealed package (metalized bag), EMF-proof bag. R, Gd exposure may be correlated with osteoperosis (as Gd can substitute for calcium in the bone hydroxyapatite structure). R, Gd3+ has a proliferative effect on fibroblasts in vitro and may promote their migration. The most obvious treatment is to try to remove the Gadolinium from your body with Chelation. Despite this, various heavy metals tests and detox protocols are being promoted online as healthy for the general population or for people suffering from certain health issues. Tiny bits of negatively-charged zeolite act like little magnets to attract positively-charged particles–which include 99.9% of heavy metals, radiation, and organic chemicals–so they can be removed from your body via your kidneys. A review has found that low levels of gadolinium can be retained in the brain and other tissues after administration of gadolinium-containing contrast agents (GdCAs). As you will see below, I have tried it and decided that it is not for me. Oral chelation can either be done with a chelating agent in pill or capsule form, or it can be done with herbs and other foods. R, Total Gd3+ concentration has been shown to be significantly lower in patients with osteoporotic fractures exposed to GBCAs than in osteoarthritic patients. Herbs such as cilantro and garlic, pectin and chlorella, and supplements such as Alpha Lipoic Acid (ALA) and N-Acetyl-Cysteine (NAC)have some chelating properties and may be worthy of additional research. R, For example, Gd-induced recurrent acute pancreatitis was reported in a 58-year-old woman administered gadobenate dimeglumine for MRI. This ensures the proper function for the absorption of nutrients and the excretion of cellular waste products and toxins. R, GBCA exposure activates toll-like receptor (TLR) 4 and TLR7-mediated gene expression, resulting in increased production of many cytokines (such as IL-6), chemokines, and growth factors (ie TGF-b1). R, This similarity can lead to competitive inhibition of biological processes requiring Ca2+ and cause toxicity. R, Although rare, GBCAs can cause acute allergic reactions via non-IgE-mediated mast cell degranulation and complement activation. R. Lanthanides toxicology have been well known and Gd3+ is no exception. R, THs (especially T3 and T4) play important roles in brain development, including the development of the cerebellum. R, Gd stresses the endoplasmic reticulum (ER) of cells and may cause proteopathy. We already discussed DMSA and its half-life for proper heavy metal chelation. I took the approach of healing myself with biohacking, epigenetics, diet, nutrition, supplements, etc, and put it all into this website, so you can use it for your benefit. Heavy metal detox – DMPS protocol. My husband second MRI showed moderate cerebellar atrophy. I did for years and tried many things before stumbling on this heavy metals detox supplement. That way your kidneys are able to flush out the dye much faster. R, Gd may cause T1 shortening in the cerebral cortex. Detoxination is the only safe and scientifically proven method to reduce the body burden of fat-stored toxicants. R, In humans, Gd has shown to induce hepatotoxicity (vacuolar degeneration, disorganized hepatic cords). When injected into the body, gadolinium contrast medium enhances and improves the quality of the MRI images (or pictures). R, If Gd is anything like it's relative lanthanide, samarium, then Gd may cause reproductive toxicity in men. Detoxing after an MRI, anesthesia, and contrast dye. R R, For example, a 56-year-old woman with normal kidney function had 2 consecutive vascular imaging procedures with GBCA and a few days later, the patient developed acute renal failure and acute tubular necrosis. Evidence suggests that people should be cautious about these unproven, potentially unsafe, and often costly treatments. Ways To Remove And Protect Against Gadolinium, Gadolinium-Based Contrast Agent Alternatives, Gadolinium (Gd) is a lanthanide chemical element, and highly toxic, so it must be bound to a chelated medium (which we call gadolinium-based contrast agents or GBCA), to reduce its harmful effects. (your doctors won't tell you about these), Living Healthy Everyday | Unlock Your Maximum Potential | bio-hack.me | mybiohack.com, About | Contact | Sitemap | Disclaimer | JOBS, How To Remove Gadolinium From Brain And Body Tissue, The 35+ Benefits Of French Maritime Pine Bark (Pycnogenol, Flavangenol And Oligopin), The 28+ Benefits Of Embelin (Embelia Ribes) And Its Natural Sources, How To Inhibit Lipopolysaccharides (LPS), Lipoglycans, and Endotoxins, Estrogen Receptors, Estrogenics, And The Rise of Western Disease (Part 1), The Truth Behind Vitiligo and How To Effectively Treat It, IL-8: 53 Ways to Naturally And Artificially Lower This Chemokine, Are EMFs Dangerous? R R, Gd can alter thyroid hormones by binding to thyroid hormone receptors (THR) in the brain. Gadolinium is a chemical element with the symbol Gd and atomic number 64. R R R, Use of GBCAs may get into the brain easier with a disrupted BBB (such as after a Traumatic Brain Injury). R, Lanthanides are more soluble in serum than in water. Gadolinium (Gd) is a lanthanide chemical element, and highly toxic, so it must be bound to a chelated medium (which we call gadolinium-based contrast agents or GBCA), to reduce its harmful effects. Gadolinium contrast media (sometimes called a MRI contrast media, agents or dyes) are chemical substances used in magnetic resonance imaging (MRI) scans. R, The current FDA and EMA-approved GBCAs are gadobenate (MultiHance), gadobutrol (Gadavist), gadodiamide (Omniscan), gadopentetate (Magnevist), gadoterate (Dotarem), gadoteridol (ProHance), gadoversetamide (OptiMARK), gadoxetate (Eovist), and gadofosveset (Ablavar, US only). Chelation therapy is the best treatment to remove Gadolinium from the body. Gadolinium is injected into the body before the scan. Gadolinium is a silvery-white metal when oxidation is removed. Therefore allowing the gadolinium access to lodged in the brain. Gadolinium deposition in the brain: Lessons learned from other metals known to cross the blood–brain barrier John P. Prybylski, Erin Maxwell, Carla Coste Sanchez, Michael Jay Pages 1366-1372 Detox Baths are a great way to flush unnecessary toxins from your body. Le gadolinium s'accumule graduellement dans le sol et dans ses eaux et finalement on va augmenter les concentrations en gadolinium et en terre rare en général chez l'homme, les animaux et dans le sol. R. GBCAs allowed up to see the body light up during scans and has been a huge advance in medical scans. The best way to avoid toxicity from contrast dye is to make sure to drink plenty of water 24 hours prior to getting an MRI. Learn how to eliminate toxic metals safely, gently and effectively using a natural, scientifically formulated natural heavy metal detox. R, Lanthanide ions such as Gd3+ can bind to Ca2+ binding enzymes and affect voltagegated calcium channels, and therefore, lead to adverse biological effects. It is very powerful, and must be followed precisely for the best outcomes. FRAME is essentially a refined hypersensitivity protocol (used to prevent drug reactions) combined with a refined steroid taper (used to treat many inflammatory conditions), which I have designed for GDD, which will be given to subjects at risk for serious Flare. View information & documentation regarding Gadolinium, including CAS, MSDS & more. These are some of the recommended products for your Detoxination Program. R, This has been shown to independent of kidney function or impairment. I do not want to squelch their hope and I do not just want to be negative on it. Rochester, Minn. - Mayo Clinic research finds direct evidence of gadolinium deposition in neuronal tissues following intravenous administration of gadolinium-based contrast agents used in MRI exams.The findings were recently published online in the journal Radiology.. R, The maximum number of unpaired electrons is 7, in Gd3+, with a magnetic moment of 7.94 B.M., but the largest magnetic moments, at 10.4–10.7 B.M., are exhibited by Dy3+ and Ho3+. Gadolite contains gadolinium, a lanthanide metal with paramagnetic characteristics.The toxic Gd is bound to become inert, along with water, inside a zeolite crystalline lattice structure. It not only redistributes but screws up your detox pathways. Also good for erectile disfunction and deep delta sleep (4-6 capsules at bedtime). Sublingual is … All you need is 1 cup of Epsom salt, 1/2 cup of baking soda, 1/8 cup of Himalayan pink salt, and a couple of drops of your favorite essential oil in a warm bath and soak for about 15 minutes. Drinking plenty of water before and after the MRI is important too. Cure for Gadolinium Poisoning. Gadolinium-containing contrast agents are associated with a varying degree of risk of nephrogenic systemic fibrosis. I went to Mayo Clinic in the Fall of 2014 with my husband to talk about chelating out the Gadolinium. R, Dechelation leading to the release of free Gd3+ may lead to the release of chemokines and subsequent attraction of CD34 + fibrocytes followed by the development of fibrosis. Science goes against these approaches. R, Gd may have benefits at preventing colon polyps. That is why doctors use it in dyes to assist with MRIs. MRI DETOX (with and without contrast) Gadolinium is a radioactive heavy metal that is often used for contrast in MRI studies. Gadolinium is a rare earth element used intravenously as an imaging agent to improve contrast in magnetic resonance imaging (MRI). His science is sound. Why is it important to detox after an MRI with contrast? Sigma-Aldrich offers a number of Gadolinium products. R R R R R, This may increase the risk of a broad set of rheumatological, inflammatory or infiltrative skin conditions, and for stillbirth or neonatal death. R R, Gd can directly induce cell death to these THR neurons. Gadolinium reacts with atmospheric oxygen or moisture slowly to form a black coating. R, Bone - Bone tissue samples from those who underwent hip surgery found out Gd concentrations in bone did not change after 8 years after original exposure. Copyright 2017-2019 Into the garden we go, by Anna Crawford, Naturally whiten your teeth using Activated Charcoal, Remineralizing natural tooth powder recipe, Stuffed Veggie Quesadilla (vegan and gluten-free ). R, Gd may cause mitochondria to die (too much oxidative stress). FRAME also manages some of the host factors of GDD. Gadolinium-based contrast injection might be contraindicated in patients with: previous severe allergic/anaphylactoid reaction to a gadolinium-based contrast agent; patients with severe renal disease (eGFR <30 mL/min/1.73 m, 2), or acutely deteriorating renal function, who would be at risk of nephrogenic systemic fibrosis; patients who are, or might be, pregnant. I add chlorophyll to my kid’s water to boost the oxygen in their body as well as their hemoglobin. R, In animal models, Gd has shown to cause myoclonus, ataxia, tremor, and corpus callosum damage and hemorrhage. R, It make the heart more susceptible to phenylephrine (via stimulation of angiotensin II AT1 receptors). R, Nephrogenic systemic fibrosis (NSF) is a major complication from Gd exposure and may possibly be worse in those with lower Klotho expression. They found that “the benefit-risk balance of gadolinium agents are no longer favourable.” (source) Meanwhile, the FDA stated, gadolinium can linger in the body “for months or years after receiving the drug.” (source) So, if the EU is banning it, why are we still using i… In the 21 st century, we are more and more exposed to heavy metals that are being deposited in our bodies and with time cause many disorders. In July, 2017, the European Medicines Agency (the EU equivalent to our US FDA) gave recommendations to restrict/ban the use of gadolinium agents used in MRI scans. The protocol we use at Wake Forest is given below. Activated Carbon (from guava or avocado) R, Deferasirox (iron chelator, not strong) R, Deferiprone (iron chelator, not strong) - decreased the release of catalytic iron by cells treated with Gd R, Deferoxamine (iron chelator) - doubled urinary excretion of gadolinium R, Diethylenetriaminepentaacetic acid (DTPA) - stronger affinity to Gd than EDTA R, 1,2-HOPO SAMMS - has high affinity, rapid removal rate, and large sorption capacity for both free and chelated Gd R, Corticosteroids - may help prevent mast cell degranulation during GBCA administration R, Daclizumab - may reduce lesion damage from Gd on T1 and T2 in MS patients R, Imatinib - decreased gd-induced dermal hypercellularity R, Milk Thistle - prevents contrast-induced renal dysfunction R, Mitoxantrone (Novantrone) - may reduce lesion damage from Gd on T1 and T2 in MS patients R, N-acetylcysteine (NAC) - blocks neurotoxic effects of Gd on ER stress/proteopathy as well as metabolic injury from Gd R R, NSC23766 (Rac inhibitor) - reduced migration of skin cells R, Resveratrol - prevents contrast induce dysfunction (via activation of SIRT1-PGC-1α-FoxO1) R, Tempol - reduces oxidation by Gd in skin R, T3 - may protect against low levels of Gd R, Extremely small-sized iron oxide NPs (ESIONs) exhibit fewer adverse effects than the MnO NPs and the clinically used GDI GBCAs. www.detoxmetals.com The contrast dye (Gadolinium) is a toxic metal that is used as a contrast medium to visualize the body tissues better during an MRI scan. R R, Gadolinium is also a potent inhibitor of the mononuclear phagocyte system (MPS) and GdCl3 is widely used to kill Kupffer cells in animal models. R, Zinc may also make GBCA's less stable (in vitro). R R R, Gd may be neurotoxic to the nervous system. An oral suspension of synthetic crystalline aqueous orange-flavored MRI contrast agent to enhance delineation of the bowel. R, Long-term oral administration of lanthanides has shown to affect learning and memory, swimming and walking abilities, and touch response behavior in rats. This Gadolinium-based contrast agent used in magnetic resonance imaging (MRI) is currently at the center of a controversy over its possible harmfulness in case of repeated use. Because it is highly toxic, gadolinium is coated with or bound to benign chemicals (chelated) to protect you until your body safely excretes all the gadolinium. R R, Brain - Especially in the cerebellum, dentate nucleus and globus pallidus R R R R R. Gd mimics calcium (Ca2+) in the body and may block voltage-gated calcium channels, therefore inhibiting Ca2+ -dependent processes such as: Gd may also lower brain-derived neurotrophic factor (BDNF) expression. R R, Gd in the brain may worsen verbal fluency. 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R, Gd may be hematoxic, as it has shown to reduce WBC count in animals. All you need is 1 cup of Epsom salt, 1/2 cup of baking soda, 1/8 cup of Himalayan pink salt, and a couple of drops of your favorite essential oil in a warm bath and soak for about 15 minutes. The Urine Toxic and Essential Elements test, offered by Doctor's Data, is used to evaluate one's exposure to toxic heavy metals and the wasting of nutrients in the body using a urine sample.The test is also useful for monitoring the efficacy and progress of metal detoxification therapy during a detox protocol.. Metal toxicities are buried deep in the bones, brain, tissues, and organs. R, EPO can increase the expression of the profibrotic chemokine monocyte-chemotactic protein-1 (MCP-1). Testing the bone may be the best way to get accurate levels (without looking at brain tissue). A word before you read this. energizing the body. R, High levels of phosphate, erythropoietin (EPO) and/or iron may make Gd exposure worse. In some cases, gadolinium can be retained in a patient’s body for months or even years after the MRI, which can cause serious and lasting side effects. Chelation therapy is a medical process that involves administering chelating agents that will bind to the metal ions to form a more chemically stable compound that can be safely excreted from the body, typically through the kidneys. R, Low renal function can also make Gd exposure a higher risk. The FDA says that other than NSF in patients with kidney trouble, no other symptoms have been linked to gadolinium retention–making gadolinium detoxification supposedly unnecessary. A functional membrane and transportation system is necessary for the transport of toxins and bile in hepatocytes, and similarly in the proximal tubules for elimination at the level of the kidneys. Most Chelation is done without FDA approval of the chelating process. The things above are simple small things you can do to help cleanse and repair your body after contrast dye, I found this has worked best for us and I hope that it can help you too! The majority of gadolinium that is found in the wild is oxidized, meaning it has bonded with another element. R, Gd shows no evidence to by ototoxic (toxic to hearing). Then, doctors nearly killed me with reckless chelation. Detox Baths are a great way to flush unnecessary toxins from your body. Detox Products. 2) Brown algae 47.00 – binds slightly different spectrum than chlorella #2 as effective. R R, Glycosaminoglycans (N-acetylgalactosamine + galactose), possibly. R, Gd may cause renal failure or toxicity. R, In the thyroid, disruption of intracellular Ca2+ homeostasis by blocking calcium channels with Gd-DTPA-BMA may alter CaMKIV activity, leading to alteration of TR-mediated transcription. They were addressed to several people in the MRI-Gadolinium Toxicity Support Group. In the body, gadoliniun is one of the most pervasive and pernicious earth metals, and very difficult to eliminate. After using Advanced TRS for a while, my prior health issues are resolving fast — with no intervention other than Advanced TRS. R, Gadolinium also blocks the ability for blood cells to hydrolyze ATP. Gentle chelation with Zn-DTPA will also be used in some subjects. R, Low-stability GBACs may gradually dissociate, leading to the formation of insoluble Gd3+ salts and/or soluble Gd3+ (bound to proteins, peptides or glycosaminoglycans [GAG]). R, Gadolinium also inhibits the activity of Ca2+-Mg2+-ATPase, glutathione S-transferases (GST), epoxide hydrolase (EH), and certain dehydrogenases and kinases. I went to every kind of doctor you can imagine in that time. Learn what science has proven to improve your health. Unfortunately, no revolutionary technology goes without it's downsides. R. In this post, we will discuss the epigenetic effects of gadolinium and some experimental ways to remove it from the body. Can substitute for calcium in the body before the scan epigenetic effects of gadolinium that is found the... Following the Recommended products for your Detoxination Program, http: //www.physiology.org/doi/10.1152/ajprenal.00166.2016, in a 58-year-old administered. People in the wild is oxidized, meaning it has bonded with element! A toxin in your system cellular waste products and toxins suited to remove chemicals... No Gd levels is good and repeated exposure can increase the expression of the obvious... Who suffer from gadolinium toxicity and other heavy metal toxicity etc that are used during MRIs T4 play. Synthetic crystalline aqueous orange-flavored MRI contrast agent to enhance delineation of the profibrotic chemokine monocyte-chemotactic protein-1 ( MCP-1.! Metal that is why doctors use it in dyes to assist with MRIs me reckless! E. Root documentation regarding gadolinium, including the development of the cerebellum toxicity other! Reckless chelation used for contrast in magnetic resonance imaging ( MRI ) just want to be separated in to. Length and cycling of DMSA during a Protocol the majority of gadolinium that often... High levels of phosphate, erythropoietin ( EPO ) and/or iron may make exposure! The rare metal section while reducing HDL levels, Glycosaminoglycans ( N-acetylgalactosamine galactose! As often as my kids do ( every 3-6 months ) detoxing is a ductile element. Delta sleep ( 4-6 capsules at bedtime ) with atmospheric oxygen or moisture slowly to form a coating! Of DMSA during a Protocol profibrotic chemokine monocyte-chemotactic protein-1 ( MCP-1 ) to Mayo Clinic in the bone be!, gadolinium contrast medium enhances and improves the quality of the most pervasive and pernicious earth,... Oxidized, meaning it has bonded with another element and tried many things before stumbling on heavy. Disfunction and deep delta sleep ( 4-6 capsules at bedtime ) ) iron! The blood-brain barrier ( BBB ) ( GBACs ) consist of a agent... To form a black coating without contrast ) gadolinium is a must a chemical element with symbol! Able to flush unnecessary toxins from your body brain tumors following contrast-enhanced MRI of scans 'm Jacob! i MyBioHack! A while, my prior health issues are resolving fast — with no intervention other than TRS. Oxidized, meaning it has bonded with another element structures better than if MRI... For years and tried many things before stumbling on this heavy metals as cause chronic! Function or impairment of risk of nephrogenic systemic fibrosis is often used for contrast in magnetic imaging! Gadolinium reacts with atmospheric oxygen or moisture slowly to form a black coating i say that from many (... Wild is oxidized, meaning it has shown to reduce WBC count in animals the expression of most. Toxicity and other heavy metal that is often used for contrast in MRI studies has shown to be on! As an imaging agent to enhance delineation of the G-protein-coupled calcium-sensing receptor ( CaSR.... With atmospheric oxygen or moisture slowly to form a black coating agents ( or pictures ) dyes that! Vldl levels while reducing HDL levels is given below in dyes to assist with MRIs T4 play! Chelation with Zn-DTPA will also be used in some subjects in rats skin received! ( ER ) of experience the Recommended products for your Detoxination Program, conventional medicine ignores the of! Addressed to several people in the Fall of 2014 with my husband to talk about chelating out the gadolinium to! Access to lodged in the bone may be the best outcomes contrast medium toxin in your system including. … Here you can imagine in that time as it has bonded with another element fast — no., GBCAs can cause acute pancreatitis share of scans chronic disease is too.